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KBI兩類非人靈長類肥胖及并發(fā)癥模型為評價多種靶點(diǎn)新藥助力

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日期：2023-12-08 17:57:15
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我國成年人患肥胖癥及超重已達(dá)50%人群, 而肥胖癥是代謝性疾病 (如糖尿病、非酒精性脂肪肝病)、心血管疾病 (如高血壓、中風(fēng)、動脈粥樣硬化、心機(jī)梗塞) 及一些腫瘤發(fā)生和發(fā)展的危險因素 (LANCET Diab & Endocrinol 2021;9:373-392)。昆明科靈生物科技有限公司 (KBI) 在食蟹猴建立起大規(guī)模自發(fā)性和高脂飲食誘導(dǎo)兩類肥胖模型，伴隨不同程度的上述疾病，與人類過食和高脂飲食兩大成因高度契合 (見下圖)。

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